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| Cat.No | ACP01946 | Target Name | PATL1 |
|---|---|---|---|
| Target Synonyms | PAT1-like protein 1;Protein PAT1 homolog b;Pat1b;hPat1b | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Mol Weight | 89.6 kDa |
| Protein Length | Full length | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86TB9 |
|---|
Uniprot Id
Q86TB9
Target Species
Human
Target Name
PATL1
Target Full Name
Protein PAT1 homolog 1
Target Function
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly.; (Microbial infection) In case of infection, required for translation and replication of hepatitis C virus (HCV).
Target Subcellular Location
Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle.
Target Protein Families
PAT1 family
Target Tissue Specificity
Ubiquitous.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
hPat1b; OK/KNS-cl.5; PAT1-like protein 1; Pat1b; PATL1; PATL1_HUMAN; protein associated with topoisomerase II homolog 1 ; Protein PAT1 homolog 1; Protein PAT1 homolog b
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