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| Cat.No | ACP01054 | Target Name | SSX1 |
|---|---|---|---|
| Target Synonyms | (Cancer/testis antigen 5.1)(CT5.1)(Synovial sarcoma, X breakpoint 1) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-188aa |
| Mol Weight | 34.9 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16384 |
|---|
Uniprot Id
Q16384
Target Species
Human
Target Name
SSX1
Target Full Name
Protein SSX1
Target Function
Could act as a modulator of transcription.
Target Involvement
A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
Target Protein Families
SSX family
Target Tissue Specificity
Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Cancer/testis antigen 5.1; Cancer/testis antigen family 5 member 1; CT5.1; MGC150425; MGC5162; Protein SSX1; sarcoma; synovial; X chromosome related 1; SSRC; SSX1; SSX1_HUMAN; Synovial sarcoma; Synovial sarcoma; X breakpoint 1 ; X breakpoint 1
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