Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP10386 | Target Name | ZYG11B |
|---|---|---|---|
| Target Synonyms | cell cycle regulator; ZYG11; Zyg11b, KIAA1730; Protein zyg-11 homolog B; ZY11B_HUMAN; zyg-11 family member B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-744 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9C0D3 |
|---|
Uniprot Id
Q9C0D3
Target Species
Human
Target Name
ZYG11B
Target Full Name
Protein zyg-11 homolog B
Target Function
Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZER1 to target substrates bearing N-terminal glycine degrons for proteasomal degradation. Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation.
Target Protein Families
Zyg-11 family
Target Synonyms
KIAA1730; Protein zyg-11 homolog B; ZY11B_HUMAN; zyg-11 family member B, cell cycle regulator; ZYG11; Zyg11b
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
