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| Cat.No | ACP15730 | Target Name | ASXL2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q76L83 |
|---|
Uniprot Id
Q76L83
Target Species
Human
Target Name
ASXL2
Target Full Name
Putative Polycomb group protein ASXL2
Target Function
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3
Target Involvement
Shashi-Pena syndrome (SHAPNS)
Target Subcellular Location
Nucleus.
Target Protein Families
Asx family
Target Synonyms
additional sex combs like 2 (Drosophila); Additional sex combs like 2; Additional sex combs like protein 2; Additional sex combs-like protein 2; ASXH2; ASXL 2; ASXL2; ASXL2_HUMAN; DKFZp686C1968; FLJ10898; KIAA1685; Polycomb group protein ASXH2; Putative Polycomb group protein ASXL2; SHAPNS
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