Home Products Recombinant Human Pyrroline-5-carboxylate reductase 2 (PYCR2)

Recombinant Human Pyrroline-5-carboxylate reductase 2 (PYCR2)

ACP14722

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP14722	Target Name	PYCR2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-320	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96C36

Background Information

Uniprot Id

Q96C36
Target Species

Human
Target Name

PYCR2
Target Full Name

Pyrroline-5-carboxylate reductase 2
Target Function

Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Involved in cellular response to oxidative stress.
Target Involvement

Leukodystrophy, hypomyelinating, 10 (HLD10)
Target Subcellular Location

Cytoplasm. Mitochondrion.
Target Protein Families

Pyrroline-5-carboxylate reductase family
Target Tissue Specificity

Detected in erythrocytes (at protein level). Expressed in fetal brain.
Target Synonyms

1810018M05Rik; FLJ54750; Leftb; OTTHUMP00000035614; P5C reductase 2; P5CR 2; P5CR2; P5CR2_HUMAN; PYCR 2; PYCR2; Pyrroline 5 carboxylate reductase 2; Pyrroline 5 carboxylate reductase family member 2; Pyrroline 5 carboxylate reductase isoform; Pyrroline-5-carboxylate reductase 2; RP4-559A3.4
Target Background

This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene.

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Recombinant Human Pyrroline-5-carboxylate reductase 2 (PYCR2)

Specifications

Immunogen Information

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