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| Cat.No | ACP21555 | Target Name | RASGRF2 |
|---|---|---|---|
| Target Synonyms | GRF2; Ras guanine nucleotide exchange factor 2; Ras protein specific guanine nucleotide releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2; RASGRF2; RGRF2_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14827 |
|---|
Uniprot Id
O14827
Target Species
Human
Target Name
RASGRF2
Target Full Name
Ras-specific guanine nucleotide-releasing factor 2
Target Function
Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
Target Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Tissue Specificity
Widely expressed with higher expression in brain, followed by heart, lung, pancreas and kidney. Detected in placenta. Expressed in brain and lung (at protein level).
Target Synonyms
GRF2; Ras guanine nucleotide exchange factor 2; Ras protein specific guanine nucleotide releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2; RASGRF2; RGRF2_HUMAN
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