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| Cat.No | ACP07774 | Target Name | REEP6 |
|---|---|---|---|
| Target Synonyms | REEP6; C19orf32; DP1L1; Receptor expression-enhancing protein 6; Polyposis locus protein 1-like 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96HR9 |
|---|
Uniprot Id
Q96HR9
Target Species
Human
Target Name
REEP6
Target Full Name
Receptor expression-enhancing protein 6
Target Function
Required for correct function and survival of retinal photoreceptors. Required for retinal development. In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis. May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane.
Target Involvement
Retinitis pigmentosa 77 (RP77)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein.
Target Protein Families
DP1 family
Target Tissue Specificity
Expressed in circumvallate papillae and testis. Expressed in the retina. Isoform 1 is predominantly present in mature optic cups. Isoform 1 expression is confined to the cell body and inner segment of developing rod photoreceptor cells.
Target Synonyms
REEP6; C19orf32; DP1L1; Receptor expression-enhancing protein 6; Polyposis locus protein 1-like 1
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