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| Cat.No | ACP10510 | Target Name | ARHGAP20 |
|---|---|---|---|
| Target Synonyms | ARHGAP20; KIAA1391; Rho GTPase-activating protein 20; Rho-type GTPase-activating protein 20 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P2F6 |
|---|
Uniprot Id
Q9P2F6
Target Species
Human
Target Name
ARHGAP20
Target Full Name
Rho GTPase-activating protein 20
Target Function
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Target Involvement
A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL) (PubMed:15543602). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes (PubMed:15543602).
Target Tissue Specificity
Expressed predominantly in the brain. Lower expression is found in lymph nodes.
Target Synonyms
ARHGAP20; KIAA1391; Rho GTPase-activating protein 20; Rho-type GTPase-activating protein 20
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