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| Cat.No | ACP17389 | Target Name | ARHGAP29 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q52LW3 |
|---|
Uniprot Id
Q52LW3
Target Species
Human
Target Name
ARHGAP29
Target Full Name
Rho GTPase-activating protein 29
Target Function
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
Target Tissue Specificity
Widely expressed. Highly expressed in skeletal muscle and heart. Expressed at intermediate level in placenta, liver and pancreas. Weakly expressed in brain, lung and kidney.
Target Synonyms
ARHGAP 29; Arhgap29; ARHGAP29 protein; MGC166097; PARG 1; PARG1; PTPL1 associated RhoGAP 1; PTPL1-associated RhoGAP protein 1; RHG29_HUMAN; Rho GTPase activating protein 29; Rho GTPase activating protein 29 isoform CRA_a; Rho GTPase activating protein 29 isoform CRA_b; Rho GTPase-activating protein 29; Rho-type GTPase-activating protein 29
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