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| Cat.No | ACP20524 | Target Name | ARHGEF15 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O94989 |
|---|
Uniprot Id
O94989
Target Species
Human
Target Name
ARHGEF15
Target Full Name
Rho guanine nucleotide exchange factor 15
Target Function
Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
Target Subcellular Location
Cell projection, dendrite.
Target Tissue Specificity
Expressed in the vascular smooth muscle of coronary artery.
Target Synonyms
ARGEF15; ARHGEF15; ARHGF_HUMAN; E5; Ephexin-5; Ephexin5; FLJ13791; KIAA0915; MGC44868; Rho guanine exchange factor 15; Rho guanine nucleotide exchange factor (GEF) 15; Rho guanine nucleotide exchange factor 15; Vsm RhoGEF; Vsm-RhoGEF
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