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| Cat.No | ACP13622 | Target Name | TRMT10A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-339 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TBZ6 |
|---|
Uniprot Id
Q8TBZ6
Target Species
Human
Target Name
TRMT10A
Target Full Name
tRNA methyltransferase 10 homolog A
Target Function
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
Target Involvement
Microcephaly, short stature, and impaired glucose metabolism 1 (MSSGM1)
Target Subcellular Location
Nucleus. Nucleus, nucleolus.
Target Protein Families
Class IV-like SAM-binding methyltransferase superfamily, TRM10 family
Target Tissue Specificity
Expressed in embryonic and fetal brain. It is expressed throughout the dorsal telencephalon at 8 and 11 weeks of gestation, with highest expression in ventricular zone and marginal zone. Detected in cerebellar cortex and nuclei, but not in dorsal telencep
Target Synonyms
FLJ20325; MGC27034; OTTHUMP00000220442; OTTHUMP00000220443; RG9D2_HUMAN; RG9MTD 2; Rg9mtd2; RNA (guanine-9-) methyltransferase domain containing 2; RNA (guanine-9-)-methyltransferase domain-containing protein 2; RNA (guanine-9-)methyltransferase domain containing protein 2; TRM10
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