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Recombinant Human RUN and FYVE domain-containing protein 1 (RUFY1)

ACP14028

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Specifications

Cat.No	ACP14028	Target Name	RUFY1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-708	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96T51

Background Information

Uniprot Id

Q96T51
Target Species

Human
Target Name

RUFY1
Target Full Name

RUN and FYVE domain-containing protein 1
Target Function

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Target Subcellular Location

Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Target Tissue Specificity

Broadly expressed, with highest levels in lung, testis, kidney and brain.
Target Synonyms

3000002E04Rik; FLJ22251; FYVE finger protein EIP1; FYVE-finger protein EIP1; La binding protein 1; La-binding protein 1; OTTHUMP00000161521; Rab4 interacting protein; Rab4-interacting protein; RABIP4; RUFY1; RUFY1_HUMAN; RUN and FYVE domain containing 1; RUN and FYVE domain-containing protein 1; RUN and FYVE domains containing protein 1; ZFYVE12; Zinc finger FYVE domain containing protein 12; Zinc finger FYVE domain-containing protein 12
Target Background

This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Recombinant Human RUN and FYVE domain-containing protein 1 (RUFY1)

Specifications

Immunogen Information

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