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| Cat.No | ACP22394 | Target Name | HPN |
|---|---|---|---|
| Target Synonyms | HPN; TMPRSS1; Serine protease hepsin; Transmembrane protease serine 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 45-417 |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P05981 |
|---|
Uniprot Id
P05981
Target Species
Human
Target Name
HPN
Target Full Name
Serine protease hepsin
Target Function
Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.
Target Subcellular Location
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
Detected in liver and kidney.
Target Synonyms
HPN; TMPRSS1; Serine protease hepsin; Transmembrane protease serine 1
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