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| Cat.No | ACP23700 | Target Name | PPP2R1B |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-601 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P30154 |
|---|
Uniprot Id
P30154
Target Species
Human
Target Name
PPP2R1B
Target Full Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Target Function
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
Target Protein Families
Phosphatase 2A regulatory subunit A family
Target Synonyms
2AAB_HUMAN; beta isoform of regulatory subunit A; protein phosphatase 2; PP2A A beta; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A; subunit A; PR65 beta isoform; PP2A; subunit A; R1 beta isoform; PPP2R1B; PPP4R1; PR65B; protein phosphatase 2 (formerly 2A); regulatory subunit A (PR 65); beta isoform; protein phosphatase 2 (formerly 2A); regulatory subunit A; beta isoform; Protein phosphatase 2; regulatory subunit A; beta; Protein phosphatase 2; structural/regulatory subunit A; beta; protein phosphatase 2; structural/regulatory subunit A; beta isoform; serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A; beta isoform; serine/threonine protein phosphatase 2A; 65 kDa regulatory subunit A; beta isoform; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Target Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
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