Recombinant Human Seven in absentia homolog 3 (SIAH3)

ACP15148

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Specifications

Cat.No	ACP15148	Target Name	SIAH3
Target Synonyms	FLJ39203; Gm912; RP11-480G1.1; Seven in absentia homolog 3; Siah-3; SIAH3; SIAH3_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-269
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IW03

Background Information

Uniprot Id

Q8IW03
Target Species

Human
Target Name

SIAH3
Target Full Name

Seven in absentia homolog 3
Target Function

Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria.
Target Subcellular Location

Mitochondrion.
Target Protein Families

SINA (Seven in absentia) family
Target Synonyms

FLJ39203; Gm912; RP11-480G1.1; Seven in absentia homolog 3; Siah-3; SIAH3; SIAH3_HUMAN

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Recombinant Human Seven in absentia homolog 3 (SIAH3)

Specifications

Immunogen Information

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