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Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 3 (SCUBE3), Truncated

ACP15185

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Specifications

Cat.No	ACP15185	Target Name	SCUBE3
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IX30

Background Information

Uniprot Id

Q8IX30
Target Species

Human
Target Name

SCUBE3
Target Full Name

Signal peptide, CUB and EGF-like domain-containing protein 3
Target Function

Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
Target Subcellular Location

Secreted. Cell surface.
Target Tissue Specificity

Highly expressed in osteoblasts. In normal lung, mainly expressed in bronchial epithelial cells. Tends to be up-regulated in lung cancer cells.
Target Research Area

Cardiovascular
Target Synonyms

CEGF3; CUB and EGF containing protein 3; CUB and EGF-like domain-containing protein 3; CUB domain and EGF like repeat containing 3; DKFZp686B09105; DKFZp686B1223; DKFZp686D20108; FLJ34743; OTTHUMP00000016250; SCUB3_HUMAN; SCUBE 3; SCUBE3; Signal peptide; Signal peptide CUB and EGF like domain containing protein 3; Signal peptide CUB domain EGF like 3

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Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 3 (SCUBE3), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 3 (SCUBE3), Truncated Now

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