Recombinant Human Sodium- and chloride-dependent GABA transporter 3 (SLC6A11), Truncated

ACP05510

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Specifications

Cat.No	ACP05510	Target Name	SLC6A11
Target Synonyms	GABT3; GAT-3; GAT3; S6A11_HUMAN; Slc6a11; Sodium- and chloride-dependent GABA transporter 3; Solute carrier family 6 member 11	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P48066

Background Information

Uniprot Id

P48066
Target Species

Human
Target Name

SLC6A11
Target Full Name

Sodium- and chloride-dependent GABA transporter 3
Target Function

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A11 subfamily
Target Tissue Specificity

Widespread distribution in the brain.
Target Synonyms

GABT3; GAT-3; GAT3; S6A11_HUMAN; Slc6a11; Sodium- and chloride-dependent GABA transporter 3; Solute carrier family 6 member 11
Target Background

The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene.

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Recombinant Human Sodium- and chloride-dependent GABA transporter 3 (SLC6A11), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Sodium- and chloride-dependent GABA transporter 3 (SLC6A11), Truncated Now

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