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| Cat.No | ACP06168 | Target Name | SLC5A12 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q1EHB4 |
|---|
Uniprot Id
Q1EHB4
Target Species
Human
Target Name
SLC5A12
Target Full Name
Sodium-coupled monocarboxylate transporter 2
Target Function
Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.
Target Subcellular Location
Apical cell membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:solute symporter (SSF) (TC 2.A.21) family
Target Synonyms
AI315119; D630015G19; DKFZp564G223; Electroneutral sodium monocarboxylate cotransporter; Low-affinity sodium-lactate cotransporter; MGC52019; RGD1311652; RP24-331J23.1; SC5AC_HUMAN; Slc5a12; SMCT2; Sodium-coupled monocarboxylate transporter 2; Solute carrier family 5 member 12
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