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Recombinant Human Sodium-dependent neutral amino acid transporter B (0)AT3 (SLC6A18), Truncated

ACP05913

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Specifications

Cat.No	ACP05913	Target Name	SLC6A18
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96N87

Background Information

Uniprot Id

Q96N87
Target Species

Human
Target Name

SLC6A18
Target Full Name

Inactive sodium-dependent neutral amino acid transporter B(0)AT3
Target Function

Does not show neutral amino acid transporter activity.
Target Involvement

Genetic variations in SLC6A18 might contribute to the disease phentotype in some individuals with iminoglycinuria or hyperglycinuria, that carry variants in SLC36A2, SLC6A19 or SLC6A20 (PubMed:19033659).
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A18 subfamily
Target Tissue Specificity

Abundantly expressed in kidney, but not in intestine.
Target Synonyms

SLC6A18; XTRP2; Inactive sodium-dependent neutral amino acid transporter B(0)AT3; Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3
Target Background

The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).

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Recombinant Human Sodium-dependent neutral amino acid transporter B (0)AT3 (SLC6A18), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Sodium-dependent neutral amino acid transporter B (0)AT3 (SLC6A18), Truncated Now

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