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| Cat.No | ACP00159 | Target Name | SMOC1 |
|---|---|---|---|
| Target Synonyms | Secreted modular calcium-binding protein 1;SMOC-1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 277-382aa |
| Mol Weight | 43.2 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H4F8 |
|---|
Uniprot Id
Q9H4F8
Target Species
Human
Target Name
SMOC1
Target Full Name
SPARC-related modular calcium-binding protein 1
Target Function
Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation.
Target Involvement
Ophthalmoacromelic syndrome (OAS)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Target Tissue Specificity
Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen.
Target Research Area
Developmental Biology
Target Synonyms
Secreted modular calcium-binding protein 1; SMOC-1; SMOC1; SMOC1_HUMAN; SPARC-related modular calcium-binding protein 1
Target Background
This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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