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| Cat.No | ACP16549 | Target Name | SASS6 |
|---|---|---|---|
| Target Synonyms | SASS6; SAS6; Spindle assembly abnormal protein 6 homolog; HsSAS-6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-657 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UVJ0 |
|---|
Uniprot Id
Q6UVJ0
Target Species
Human
Target Name
SASS6
Target Full Name
Spindle assembly abnormal protein 6 homolog
Target Function
Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification.
Target Involvement
Microcephaly 14, primary, autosomal recessive (MCPH14)
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Target Synonyms
SASS6; SAS6; Spindle assembly abnormal protein 6 homolog; HsSAS-6
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