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Recombinant Human Suppressor APC domain-containing protein 2 (SAPCD2)

ACP15352

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15352 Target NameSAPCD2
Target SynonymsSAPCD2; C9orf140; Suppressor APC domain-containing protein 2; Tumor specificity and mitosis phase-dependent expression protein; TS/MDEP; p42.3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-394
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86UD0
Background Information
  • Uniprot Id

    Q86UD0

  • Target Species

    Human

  • Target Name

    SAPCD2

  • Target Full Name

    Suppressor APC domain-containing protein 2

  • Target Function

    Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions. Negatively regulates the mitotic apical cortex localization of GPSM2. Involved also in positive regulation of cell proliferation and tumor cell growth.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Cytoplasm, cell cortex. Apical cell membrane. Cell junction, tight junction.

  • Target Tissue Specificity

    Expressed in 5-month-old fetal tissues, including stomach, intestine, colon, liver, brain, lung, heart, spleen and kidney. Undetectable in non-cancerous adult tissues. Expressed in many primary gastric carcinoma, but almost not in adjacent normal mucosa.

  • Target Synonyms

    SAPCD2; C9orf140; Suppressor APC domain-containing protein 2; Tumor specificity and mitosis phase-dependent expression protein; TS/MDEP; p42.3

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