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| Cat.No | ACP08783 | Target Name | TAS2R46 |
|---|---|---|---|
| Target Synonyms | TAS2R46; Taste receptor type 2 member 46; T2R46; Taste receptor type 2 member 54; T2R54 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 250-309aa |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P59540 |
|---|
Uniprot Id
P59540
Target Species
Human
Target Name
TAS2R46
Target Full Name
Taste receptor type 2 member 46
Target Function
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Target Protein Families
G-protein coupled receptor T2R family
Target Tissue Specificity
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed on ciliated airway epithelium.
Target Synonyms
TAS2R46; Taste receptor type 2 member 46; T2R46; Taste receptor type 2 member 54; T2R54
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