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Recombinant Human Taste receptor type 2 member 46 (TAS2R46), Truncated

ACP08783

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP08783 Target NameTAS2R46
Target SynonymsTAS2R46; Taste receptor type 2 member 46; T2R46; Taste receptor type 2 member 54; T2R54FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range250-309aa
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP59540
Background Information
  • Uniprot Id

    P59540

  • Target Species

    Human

  • Target Name

    TAS2R46

  • Target Full Name

    Taste receptor type 2 member 46

  • Target Function

    Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.

  • Target Protein Families

    G-protein coupled receptor T2R family

  • Target Tissue Specificity

    Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed on ciliated airway epithelium.

  • Target Synonyms

    TAS2R46; Taste receptor type 2 member 46; T2R46; Taste receptor type 2 member 54; T2R54

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