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| Cat.No | ACP15289 | Target Name | TBC1D1 |
|---|---|---|---|
| Target Synonyms | KIAA1108; TBC 1; TBC; TBC1 (tre 2/USP6; BUB2; cdc16) domain family; member 1; TBC1; TBC1 domain family member 1; Tbc1d1; TBCD1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86TI0 |
|---|
Uniprot Id
Q86TI0
Target Species
Human
Target Name
TBC1D1
Target Full Name
TBC1 domain family member 1
Target Function
May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells.
Target Subcellular Location
Nucleus.
Target Synonyms
KIAA1108; TBC 1; TBC; TBC1 (tre 2/USP6; BUB2; cdc16) domain family; member 1; TBC1; TBC1 domain family member 1; Tbc1d1; TBCD1_HUMAN
Target Background
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).
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