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Recombinant Human Thrombospondin type-1 domain-containing protein 7A (THSD7A), Truncated,Yeast

ACP09940

Number
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Specifications


Cat.No ACP09940 Target NameTHSD7A
Target SynonymsThrombospondin type-1 domain-containing protein 7A; THS7A_HUMAN; Thsd7aFormLiquid or Lyophilized powder
Expression SystemYeastProtein Lengthpartial protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UPZ6
Background Information
  • Uniprot Id

    Q9UPZ6

  • Target Species

    Human

  • Target Name

    THSD7A

  • Target Full Name

    Thrombospondin type-1 domain-containing protein 7A

  • Target Function

    Plays a role in actin cytoskeleton rearrangement.; The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism.

  • Target Subcellular Location

    [Thrombospondin type-1 domain-containing protein 7A]: Cell membrane; Single-pass type I membrane protein. Cell projection.; [Thrombospondin type-1 domain-containing protein 7A, soluble form]: Secreted.

  • Target Tissue Specificity

    Detected on kidney podocytes along the glomerular capillary wall (at protein level).

  • Target Synonyms

    Thrombospondin type-1 domain-containing protein 7A; THS7A_HUMAN; Thsd7a

  • Target Background

    The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis.

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