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| Cat.No | ACP16198 | Target Name | THADA |
|---|---|---|---|
| Target Synonyms | THADA; GITA; KIAA1767; Thyroid adenoma-associated protein; Gene inducing thyroid adenomas protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6YHU6 |
|---|
Uniprot Id
Q6YHU6
Target Species
Human
Target Name
THADA
Target Full Name
tRNA (32-2'-O)-methyltransferase regulator THADA
Target Involvement
Chromosomal aberrations involving THADA have been observed in benign thyroid adenomas. Translocation t(2;3)(p21;p25) and translocation t(2;7)(p21;p15); the sequences derived from chromosomes 3p25 and 7p15 do not appear to include a coding region and the fusion events probably result in truncated THADA proteins.
Target Protein Families
THADA family
Target Tissue Specificity
Expressed in pancreas, adrenal medulla, thyroid, adrenal cortex, testis, thymus, small intestine and stomach.
Target Synonyms
THADA; GITA; KIAA1767; Thyroid adenoma-associated protein; Gene inducing thyroid adenomas protein
Target Background
This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis.
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