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Recombinant Human Transcription factor MafA (MAFA)

ACP14830

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14830 Target NameMAFA
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-353Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8NHW3
Background Information
  • Uniprot Id

    Q8NHW3

  • Target Species

    Human

  • Target Name

    MAFA

  • Target Full Name

    Transcription factor MafA

  • Target Function

    Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, Maf subfamily

  • Target Tissue Specificity

    Expressed in the islets of Langerhans (at protein level).

  • Target Synonyms

    HMafA; Mafa; MAFA_HUMAN; Pancreatic beta cell specific transcriptional activator; Pancreatic beta-cell-specific transcriptional activator; RIPE3b1; Transcription factor MafA; Transcription factor RIPE3b1; v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian); v maf musculoaponeurotic fibrosarcoma oncogene homolog A; V-maf musculoaponeurotic fibrosarcoma oncogene homolog A

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