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Recombinant Human Transforming growth factor beta regulator 1 (TBRG1)

ACP18642

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18642 Target NameTBRG1
Target SynonymsTBRG1; NIAM; Transforming growth factor beta regulator 1; Nuclear interactor of ARF and Mdm2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-411
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ3YBR2
Background Information
  • Uniprot Id

    Q3YBR2

  • Target Species

    Human

  • Target Name

    TBRG1

  • Target Full Name

    Transforming growth factor beta regulator 1

  • Target Function

    Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    TBRG1 family

  • Target Tissue Specificity

    Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell

  • Target Synonyms

    TBRG1; NIAM; Transforming growth factor beta regulator 1; Nuclear interactor of ARF and Mdm2

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