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| Cat.No | ACP08599 | Target Name | TMEM205 |
|---|---|---|---|
| Target Synonyms | TMEM205; UNQ501/PRO1018; Transmembrane protein 205 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UW68 |
|---|
Uniprot Id
Q6UW68
Target Species
Human
Target Name
TMEM205
Target Full Name
Transmembrane protein 205
Target Function
In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
Target Protein Families
TMEM205 family
Target Tissue Specificity
Widely expressed with highest levels in pancreas, followed by adrenal gland, thyroid, liver, mammary gland, prostate, kidney, and retina; lowest levels in skeletal muscle. Overexpressed in cisplatin-resistant cancer cells (at protein level).
Target Synonyms
TMEM205; UNQ501/PRO1018; Transmembrane protein 205
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