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| Cat.No | ACP06249 | Target Name | TMEM39A |
|---|---|---|---|
| Target Synonyms | TMEM39ATransmembrane protein 39A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NV64 |
|---|
Uniprot Id
Q9NV64
Target Species
Human
Target Name
TMEM39A
Target Full Name
Transmembrane protein 39A
Target Function
Regulates autophagy by controlling the spatial distribution and levels of the intracellular phosphatidylinositol 4-phosphate (PtdIns(4)P) pools. Modulates (PtdIns(4)P) levels by regulating the ER-to-Golgi trafficking of the phosphatidylinositide phosphatase SACM1L.; (Microbial infection) Positively regulates the replication of encephalomyocarditis virus (EMCV) via autophagy-dependent pathway.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
TMEM39 family
Target Tissue Specificity
Up-regulated in brain tumor glioblastoma multiforme cells (at protein level).
Target Synonyms
TMEM39ATransmembrane protein 39A
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