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| Cat.No | ACP15164 | Target Name | TRMT2A |
|---|---|---|---|
| Target Synonyms | A, homolog of, S. cerevisiae | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-625 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IZ69 |
|---|
Uniprot Id
Q8IZ69
Target Species
Human
Target Name
TRMT2A
Target Full Name
tRNA (uracil-5-)-methyltransferase homolog A
Target Function
May be involved in nucleic acid metabolism and/or modifications.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, RNA M5U methyltransferase family
Target Synonyms
HpaII tiny fragments locus 9c protein; HTF9C; TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae); TRM2 tRNA methyltransferase 2 homolog A; TRM2A_HUMAN; TRMT2A; tRNA (uracil-5-)-methyltransferase homolog A; tRNA methyltransferase 2 homolog A; tRNA methyltransferase 2, S. cerevisiae, homolog of, A
Target Background
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene.
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