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| Cat.No | ACP10864 | Target Name | TMOD2 |
|---|---|---|---|
| Target Synonyms | TMOD2; NTMOD; Tropomodulin-2; Neuronal tropomodulin; N-Tmod | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-351 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZR1 |
|---|
Uniprot Id
Q9NZR1
Target Species
Human
Target Name
TMOD2
Target Full Name
Tropomodulin-2
Target Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
Tropomodulin family
Target Tissue Specificity
Neuronal-tissue specific.
Target Synonyms
TMOD2; NTMOD; Tropomodulin-2; Neuronal tropomodulin; N-Tmod
Target Background
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.
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