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Recombinant Human Trypsin-2 (PRSS2) (K23Q,S167G), Truncated

This Recombinant Human PRSS2 is an essential research tool for those working in the field of Cell Biology. It is expressed in the E.coli system and spans the 16-247aa region of Trypsin-2 (Anionic trypsinogen; Serine protease 2; Trypsin II) and features the K23Q and S167G mutations. To facilitate purification and detection, an N-terminal GST-tag has been incorporated, ensuring a consistently high-quality product for your experiments. Our Recombinant Human PRSS2 protein exhibits a purity greater than 90%, as determined by SDS-PAGE, and is available in both liquid and lyophilized powder forms. Rely on this exceptional protein to support your Cell Biology research, delivering consistent and outstanding results.

ACP01530

This Recombinant Human PRSS2 is an essential research tool for those working in the field of Cell Biology. It is expressed in the E.coli system and spans the 16-247aa region of Trypsin-2 (Anionic trypsinogen; Serine protease 2; Trypsin II) and features the K23Q and S167G mutations. To facilitate purification and detection, an N-terminal GST-tag has been incorporated, ensuring a consistently high-quality product for your experiments.
Our Recombinant Human PRSS2 protein exhibits a purity greater than 90%, as determined by SDS-PAGE, and is available in both liquid and lyophilized powder forms. Rely on this exceptional protein to support your Cell Biology research, delivering consistent and outstanding results.

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Specifications


Cat.No ACP01530 Target NamePRSS2
Target Synonyms(Anionic trypsinogen)(Serine protease 2)(Trypsin II)FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range16-247aa(K23Q, S167G)
Mol Weight52.4 kDaProtein LengthPartial
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP07478
Background Information
  • Uniprot Id

    P07478

  • Target Species

    Human

  • Target Name

    PRSS2

  • Target Full Name

    Trypsin-2

  • Target Function

    In the ileum, may be involved in defensin processing, including DEFA5.

  • Target Subcellular Location

    Secreted, extracellular space.

  • Target Protein Families

    Peptidase S1 family

  • Target Tissue Specificity

    Expressed in Paneth cells, at the base of small intestinal crypts.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    (Anionic trypsinogen)(Serine protease 2)(Trypsin II)

  • Target Background

    This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

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