Home Products Recombinant Human Tubulin–tyrosine ligase-like protein 12 (TTLL12)

Recombinant Human Tubulin–tyrosine ligase-like protein 12 (TTLL12)

ACP17855

Number

Order Exclusive Products Now

Request a Quote

High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP17855	Target Name	TTLL12
Target Synonyms	dJ526I14.2; FLJ41795; KIAA0153; TTL12_HUMAN; TTLL12; Tubulin tyrosine ligase like family; member 12; Tubulin--tyrosine ligase-like protein 12	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-644
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14166

Background Information

Uniprot Id

Q14166
Target Species

Human
Target Name

TTLL12
Target Full Name

Tubulin--tyrosine ligase-like protein 12
Target Function

Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
Target Subcellular Location

Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus.
Target Tissue Specificity

Expressed in the basal layer of prostate and endothelial cells. Increased expression in prostatic intraepithelial neoplasia and metastatic lesions.
Target Synonyms

dJ526I14.2; FLJ41795; KIAA0153; TTL12_HUMAN; TTLL12; Tubulin tyrosine ligase like family; member 12; Tubulin--tyrosine ligase-like protein 12

Inquire Recombinant Human Tubulin–tyrosine ligase-like protein 12 (TTLL12) Now

Full Name *

Business Email Address *

Phone

Products/Services

Catalog Number

Quantity (μg, mg, g, μl, ml, L, kit)

Address

Project Description

AbTriva respects your privacy and protects your personal data in accordance with AbTriva. For more information, please see our data protection statement. *

Submit

Recombinant Human Tubulin–tyrosine ligase-like protein 12 (TTLL12)

Specifications

Immunogen Information

Inquire Recombinant Human Tubulin–tyrosine ligase-like protein 12 (TTLL12) Now

Related Products