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Recombinant Human Tyrosine-protein kinase RYK (RYK), Truncated

ACP06533

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06533 Target NameRYK
Target SynonymsRYK; JTK5A; Tyrosine-protein kinase RYKFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP34925
Background Information
  • Uniprot Id

    P34925

  • Target Species

    Human

  • Target Name

    RYK

  • Target Full Name

    Tyrosine-protein kinase RYK

  • Target Function

    May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm.

  • Target Protein Families

    Protein kinase superfamily, Tyr protein kinase family

  • Target Tissue Specificity

    Observed in all the tissues examined.

  • Target Synonyms

    RYK; JTK5A; Tyrosine-protein kinase RYK

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