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Recombinant Human U6 snRNA-associated Sm-like protein LSm6 (LSM6)

ACP22617

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22617 Target NameLSM6
Target SynonymsLSM6U6 snRNA-associated Sm-like protein LSm6FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-80
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP62312
Background Information
  • Uniprot Id

    P62312

  • Target Species

    Human

  • Target Name

    LSM6

  • Target Full Name

    U6 snRNA-associated Sm-like protein LSm6

  • Target Function

    Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    SnRNP Sm proteins family, SmF/LSm6 subfamily

  • Target Synonyms

    LSM6U6 snRNA-associated Sm-like protein LSm6

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