Recombinant Human Ubiquitin thioesterase ZRANB1 (ZRANB1)

ACP10823

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Specifications

Cat.No	ACP10823	Target Name	ZRANB1
Target Synonyms	DKFZp762P2216; hTrabid; Trabid; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; ZRAN1_HUMAN; ZRANB1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-708
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9UGI0

Background Information

Uniprot Id

Q9UGI0
Target Species

Human
Target Name

ZRANB1
Target Full Name

Ubiquitin thioesterase ZRANB1
Target Function

Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Target Subcellular Location

Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Target Protein Families

Peptidase C64 family
Target Tissue Specificity

Widely expressed.
Target Research Area

Others
Target Synonyms

DKFZp762P2216; hTrabid; Trabid; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; ZRAN1_HUMAN; ZRANB1

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Recombinant Human Ubiquitin thioesterase ZRANB1 (ZRANB1)

Specifications

Immunogen Information

Inquire Recombinant Human Ubiquitin thioesterase ZRANB1 (ZRANB1) Now

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