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| Cat.No | ACP22051 | Target Name | TESPA1 |
|---|---|---|---|
| Target Synonyms | TESPA1; KIAA0748; HSPC257Protein TESPA1; Thymocyte-expressed positive selection-associated protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-521 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A2RU30 |
|---|
Uniprot Id
A2RU30
Target Species
Human
Target Name
TESPA1
Target Full Name
Protein TESPA1
Target Function
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
Target Subcellular Location
Cytoplasm. Endoplasmic reticulum membrane.
Target Synonyms
TESPA1; KIAA0748; HSPC257Protein TESPA1; Thymocyte-expressed positive selection-associated protein 1
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