Recombinant Human UPF0510 protein INM02 (C19orf63), Truncated

Cat.No	ACP17022	Target Name	EMC10
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP17022

Target Name

EMC10

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q5UCC4

Background Information

Uniprot Id

Q5UCC4
Target Species

Human
Target Name

EMC10
Target Full Name

ER membrane protein complex subunit 10
Target Function

Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable). Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways
Target Subcellular Location

[Isoform 1]: Endoplasmic reticulum membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Target Protein Families

EMC10 family
Target Tissue Specificity

Present in serum (at protein level). Increased expression seen in the left ventrice after myocardial infarction (at protein level). Expressed in the pituitary gland; very low levels in other brain regions.
Target Research Area

Cell Biology
Target Synonyms

Chromosome 19 open reading frame 63; emc10; EMC10_HUMAN; ER membrane protein complex subunit 10; Hematopoietic signal peptide containing membrane domain containing 1; Hematopoietic signal peptide containing membrane domain containing protein 1; Hematopoietic signal peptide containing secreted 1; Hematopoietic signal peptide-containing membrane domain-containing protein 1; HSM1; HSS1; INM02; UPF0510 protein INM02

Recombinant Human UPF0510 protein INM02 (C19orf63), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human UPF0510 protein INM02 (C19orf63), Truncated Now

Related Products