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| Cat.No | ACP11510 | Target Name | VPS37B |
|---|---|---|---|
| Target Synonyms | VPS37B; Vacuolar protein sorting-associated protein 37B; hVps37B; ESCRT-I complex subunit VPS37B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-285 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H9H4 |
|---|
Uniprot Id
Q9H9H4
Target Species
Human
Target Name
VPS37B
Target Full Name
Vacuolar protein sorting-associated protein 37B
Target Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Target Subcellular Location
Late endosome membrane; Peripheral membrane protein. Note=Recruited to the endosomal membrane in a VPS4A-dependent fashion.
Target Protein Families
VPS37 family
Target Tissue Specificity
Widely expressed. Expressed in macrophages and lymphocytes.
Target Synonyms
VPS37B; Vacuolar protein sorting-associated protein 37B; hVps37B; ESCRT-I complex subunit VPS37B
Target Background
Enables calcium-dependent protein binding activity. Involved in positive regulation of viral budding via host ESCRT complex. Located in endosome membrane; midbody; and plasma membrane. Part of ESCRT I complex.
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