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Recombinant Human WD repeat- and FYVE domain-containing protein 4 (WDFY4), Truncated

ACP06075

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06075 Target NameWDFY4
Target SynonymsWDFY4; C10orf64; KIAA1607WD repeat- and FYVE domain-containing protein 4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6ZS81
Background Information
  • Uniprot Id

    Q6ZS81

  • Target Species

    Human

  • Target Name

    WDFY4

  • Target Full Name

    WD repeat- and FYVE domain-containing protein 4

  • Target Function

    Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.

  • Target Subcellular Location

    Early endosome. Endoplasmic reticulum.

  • Target Synonyms

    WDFY4; C10orf64; KIAA1607WD repeat- and FYVE domain-containing protein 4

  • Target Background

    Predicted to be involved in autophagy. Predicted to act upstream of or within with a positive effect on CD8-positive, alpha-beta T cell activation. Predicted to act upstream of or within antigen processing and presentation and cellular response to virus. Predicted to be located in early endosome and endoplasmic reticulum.

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