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| Cat.No | ACP10968 | Target Name | WDR54 |
|---|---|---|---|
| Target Synonyms | WD repeat-containing protein 54; WDR54; WDR54_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-334 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H977 |
|---|
Uniprot Id
Q9H977
Target Species
Human
Target Name
WDR54
Target Full Name
WD repeat-containing protein 54
Target Function
When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.
Target Subcellular Location
Vesicle.
Target Tissue Specificity
Expressed in epithelial cells (at protein level). Isoform 3 expression is highly increased in colorectal cancer cells.
Target Synonyms
WD repeat-containing protein 54; WDR54; WDR54_HUMAN
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