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| Cat.No | ACP20353 | Target Name | WDR91 |
|---|---|---|---|
| Target Synonyms | HSPC049; WD repeat containing protein 91; WD repeat domain 91; WD repeat-containing protein 91; WDR 91; WDR91; WDR91_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-747 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A4D1P6 |
|---|
Uniprot Id
A4D1P6
Target Species
Human
Target Name
WDR91
Target Full Name
WD repeat-containing protein 91
Target Function
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Target Protein Families
WD repeat WDR91 family
Target Synonyms
HSPC049; WD repeat containing protein 91; WD repeat domain 91; WD repeat-containing protein 91; WDR 91; WDR91; WDR91_HUMAN
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