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Recombinant Human WD repeat domain-containing protein 83 (WDR83)

ACP12208

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12208 Target NameWDR83
Target SynonymsMAPK organizer 1; MGC4238; Mitogen activated protein kinase organizer 1 ; Mitogen-activated protein kinase organizer 1; MORG 1; WD repeat domain-containing protein 83; wdr83; WDR83_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-315
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BRX9
Background Information
  • Uniprot Id

    Q9BRX9

  • Target Species

    Human

  • Target Name

    WDR83

  • Target Full Name

    WD repeat domain-containing protein 83

  • Target Function

    Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator. May also be involved in pre-mRNA splicing.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    WD repeat MORG1 family

  • Target Synonyms

    MAPK organizer 1; MGC4238; Mitogen activated protein kinase organizer 1 ; Mitogen-activated protein kinase organizer 1; MORG 1; WD repeat domain-containing protein 83; wdr83; WDR83_HUMAN

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