Home Products Uncategorized Recombinant Human Zinc finger CCCH domain-containing protein 8 (ZC3H8)

Recombinant Human Zinc finger CCCH domain-containing protein 8 (ZC3H8)

ACP12819

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Specifications

Cat.No	ACP12819	Target Name	ZC3H8
Target Synonyms	Fliz1; Zc3h8; ZC3H8_HUMAN; Zinc finger CCCH domain containing protein 8; Zinc finger CCCH domain-containing protein 8	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-291
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8N5P1

Background Information

Uniprot Id

Q8N5P1
Target Species

Human
Target Name

ZC3H8
Target Full Name

Zinc finger CCCH domain-containing protein 8
Target Function

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Target Subcellular Location

Nucleus. Note=Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
Target Synonyms

Fliz1; Zc3h8; ZC3H8_HUMAN; Zinc finger CCCH domain containing protein 8; Zinc finger CCCH domain-containing protein 8

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Recombinant Human Zinc finger CCCH domain-containing protein 8 (ZC3H8)

Specifications

Immunogen Information

Inquire Recombinant Human Zinc finger CCCH domain-containing protein 8 (ZC3H8) Now

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