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| Cat.No | ACP19123 | Target Name | ZNF408 |
|---|---|---|---|
| Target Synonyms | EVR6; PFM14; PR domain zinc finger protein 17; PRDM17; RP72; Zinc finger protein 408; ZN408_HUMAN; ZNF408 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-720 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H9D4 |
|---|
Uniprot Id
Q9H9D4
Target Species
Human
Target Name
ZNF408
Target Full Name
Zinc finger protein 408
Target Function
May be involved in transcriptional regulation.
Target Involvement
Vitreoretinopathy, exudative 6 (EVR6); Retinitis pigmentosa 72 (RP72)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highest expression is observed in adult retina; abundantly expressed in the fetal eye. In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at
Target Synonyms
EVR6; PFM14; PR domain zinc finger protein 17; PRDM17; RP72; Zinc finger protein 408; ZN408_HUMAN; ZNF408
Target Background
The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP).
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