Ubiquitin-Conjugating Enzyme E2 D4 (UBE2D4) Reagents

Ubiquitin-conjugating enzyme E2 D4

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination.

Ubiquitin-conjugating enzyme family

Epigenetics and Nuclear Signaling

UBE2D4; UBCH5D; Ubiquitin-conjugating enzyme E2 D4; EC 2.3.2.23; E2 ubiquitin-conjugating enzyme D4; HBUCE1; Ubiquitin carrier protein D4; Ubiquitin-protein ligase D4

Enables ubiquitin conjugating enzyme activity. Involved in protein polyubiquitination. Acts upstream of or within protein ubiquitination. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus.