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Rabbit anti-Human FGF10 Polyclonal Antibody

The antibody against FGF10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-208 of human FGF10 (NP_004456.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-12552A

The antibody against FGF10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-208 of human FGF10 (NP_004456.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-12552A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFGF10
Target SynonymsLADD3; FGF10FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse stomachApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 40-208 of human FGF10 (NP_004456.1).Target SpeciesHuman
Immunogen SequenceLGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHSUniprot IDO15520
Background Information
  • Uniprot Id

    O15520

  • Target Species

    Human

  • Target Name

    FGF10

  • Target Full Name

    Fibroblast growth factor 10

  • Target Function

    Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.

  • Target Involvement

    Aplasia of lacrimal and salivary glands (ALSG); Lacrimo-auriculo-dento-digital syndrome (LADDS)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Heparin-binding growth factors family

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    BB213776 ; fd11d03; FGF 10; FGF-10; FGF10; FGF10_HUMAN; Fibroblast growth factor 10; Keratinocyte growth factor 2; KGF 2; Produced by fibroblasts of urinary bladder lamina propria; wu:fd11d03; zgc:109774

  • Target Background

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

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