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The antibody against GFPT1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 600-699 of human GFPT1 (Q06210) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against GFPT1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 600-699 of human GFPT1 (Q06210) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-14508A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GFPT1 |
| Target Synonyms | GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L; GFPT1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse large intestine, Rat lung, Rat spleen, Rat testis, RD | Application | ELISA, WB, IHC-P |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 600-699 of human GFPT1 (Q06210). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | LVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE | Uniprot ID | Q06210 |
Uniprot Id
Q06210
Target Species
Human
Target Name
GFPT1
Target Full Name
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
Target Function
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
Target Involvement
Myasthenic syndrome, congenital, 12 (CMS12)
Target Tissue Specificity
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
Target Synonyms
GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L; GFPT1
Target Background
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.
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