Rabbit anti-Human SOX4 Monoclonal Antibody

The antibody against SOX4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human SOX4 (NP_003098.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.

ADA-14550A

Number

Cat.No	ADA-14550A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	SOX4
Target Synonyms	CSS10; EVI16; SOX4	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, Jurkat(Low expression control), K-562, Mouse lung, Rat lung, SH-SY5Y	Application	ELISA, WB, IF/ICC, IP

Cat.No

ADA-14550A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

SOX4

Target Synonyms

CSS10; EVI16; SOX4

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, Jurkat(Low expression control), K-562, Mouse lung, Rat lung, SH-SY5Y

Application

ELISA, WB, IF/ICC, IP

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SOX4 (NP_003098.1).	Target Species	Human
Immunogen Sequence	AAGRSPADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNFEPGSGSHFEFPDYC	Uniprot ID	Q06945

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SOX4 (NP_003098.1).

Target Species

Human

Immunogen Sequence

AAGRSPADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNFEPGSGSHFEFPDYC

Uniprot ID

Q06945

Background Information

Uniprot Id

Q06945
Target Species

Human
Target Name

SOX4
Target Full Name

Transcription factor SOX-4
Target Function

Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif. Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Testis, brain, and heart.
Target Synonyms

CSS10; EVI16; SOX4
Target Background

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Rabbit anti-Human SOX4 Monoclonal Antibody

Specifications

Immunogen Information

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